7-keto DHEA

7-keto DHEA is used primarily to increase metabolism and promote a healthy body weight. DHEA and 7-keto DHEA are naturally formed in the body.  DHEA is made in the adrenal gland and is the precursor of 7-keto DHEA.

7-Keto DHEA can’t be converted to the steroid hormones androgen or estrogen, hence supplementation of 7-keto DHEA doesn’t affect levels of steroid hormones in the body. In fact, 7-keto DHEA may actually decrease total levels of testosterone. Body builders and men with lower testosterone levels would want to avoid.


Clinically there is some evidence1 that 7-keto DHEA may increase the body’s thermogenesis. Thermogenesis is the body’s natural method of increasing temperature and increasing our basil metabolic rate.

7-keto DHEA appears to increase2 the levels of thyroid hormone T-3, which could be helpful in weight management.

7-keto DHEA appears to support memory3 (study done on mice), with a significant benefit to memory retention. This study showed promising results and suggested, “The possible effect of 7-oxo-DHEA in human memory problems deserves investigation3 Unfortunately, as so often happens in nutritional investigation, further investigation into this potentially  inexpensive treatment for memory issues is still lacking.

Cautions, Warnings, Side Effects

Because there hasn’t been a great deal of investigation there is little evidence on the complete safety of 7-keto-DHEA. It should not be used during pregnancy and lactation. There are no reported side effects, but I have noticed that some patients have admitted to occasionally feeling agitated while taking the supplement.


In weight loss studies subjects used 100mg of 7-keto DHEA twice daily. Personally I limit dosages for patients to 25-100 mg per day.

If you have a thyroid problem and are being tested for T3 levels and are taking 7-keto DHEA you may see your test results elevated.

  1. Lardy H, Partridge B, Kneer N, Wei Y. Ergosteroids: induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone. Proc Natl Acad Sci U S A 1995;92:6617-9.
  2. Colker CM, Torina GC, Swain MA, Kalman DS. Double-Blind Study Evaluating the Effects of Exercise Plus 3-Acetyl-7-oxo-dehydroepiandrosterone on Body Composition and the Endocrine System in Overweight Adults. Abstract presented at 2nd ASEP Annual Meeting, October 14-16, 1999, and published in Journal of Exercise Physiology online, Volume 2 Number 4 October 1999
  3. Shi J, Schulze S, Lardy HA. The effect of 7-oxo-DHEA acetate on memory in young and old C57BL/6 mice. Steroids 2000;65:124-9.

I like this low dosage 7-keto DHEA:

7-Keto 25mg 90 VegiCaps by NOW Foods

Save 15% with coupon code KETO1 till May 31 2011


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About John Montague DC

John Montague DC is the owner of WebVitamins. He is active in the industry and is currently president of the NPA East.


  1. Heikanila says:

    Does it work immediately if I take 7-keto DHEA?

    • Anonymous says:

      My wife just started taking it and was quite pleased to notice an increase in energy. However it does take time to see long term results.


  2. Thanks for explaining the usage of the medicine.. I am glad I visited here and come to know about it.. Its a great resource for me..

  3. Primrose_lin says:

    Does 7-keto DHEA have side effect?

    • Anonymous says:

      There are no reported side-effects or interactions with drugs or medication. However, research is limited so it is possible there are some that we just aren’t aware of.


  4. This is the first time I’ve read about 7-keto DHEA. It seems like it might be very helpful.

  5. Mlzhuo says:

    Will it bounce back if I stop taking 7-keto DHEA

    • Anonymous says:

      I suspect that when you discontinue it would. However the study didn’t check so that is just a guess.


  6. Suom1002 says:

    Does 7-keto DHEA work for all ages

    • Anonymous says:

      I don’t think 7-keto DHEA is something everyone should use. I would never prescribe it for a younger person unless I saw specific issues on a blood test.


  7. Sami1204 says:

    May I take 7-keto DHEA with other vitamins at the same time, Such as vitamin C

  8. Timo2048 says:

    Your price of 7-keto DHEA is the cheapest that I’ve ever found online so far

  9. Dan_mel138 says:

    I am overweight, how long may I lose 5 pounds if I take 7-keto DHEA?

    • jmontague says:

      There is really no answer as everyone is different. I don’t think 7-keto should be used only for a diet. A good diet is one in which you change eating habits over time.


  10. Bill_jj213 says:

    7-keto DHEA is a really good supplement. I have taken it for a while, and my health is better now.

  11. Does 7 Keto DHEA have raspberry extract in it?

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