In crush injury, how L-carnitine maintains the normal structure of the sciatic nerve Several studies have demonstrated that L-carnitine exhibits neuroprotective effects on injured sciatic nerve of rats with diabetes mellitus. Dr. Ümmü Zeynep Avsar, Faculty of Medicine, Ataturk University, Turkey and his team proposed a hypothesis that L-carnitine exhibits neuroprotective effects on injured sciatic nerve of rats. Rat sciatic nerve was crush injured by a forceps and exhibited degenerative changes. After intragastric administration of 50 and 100 mg/kg L-carnitine for 30 days, axon area, myelin sheath area, axon diameter, myelin sheath diameter, and numerical density of the myelinated axons of injured sciatic nerve were similar to normal, and the function of injured sciatic nerve also improved significantly. Learn more here: http://www.medicalnewstoday.com/releases/279870.phpby
Schizophrenia is a mental health condition that affects around 2.4 million American adults. It is characterized by hallucinations, delusions, dysfunctional thoughts and agitated body movements. Exactly what causes the condition is unclear, although previous studies have suggested that imbalances of chemical reactions in the brain, genetics and environmental factors may play a part. The researchers of this latest study, including Ahmad Esmaillzadeh, PhD, of the Isfahan University of Medical Sciences in Isfahan in Iran, set out to investigate whether there is an association between vitamin D deficiency and schizophrenia.
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A diet rich in omega-3 fatty acids may help cut your risk for the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a new study suggests. These fatty acids — found most commonly in certain fish — are known to help reduce inflammation and oxidative stress on cells. Both of those processes can damage nerve tissue, according to the study authors. Inflammation and oxidative stress have long been linked with ALS, the study authors said, so any nutrient that fights those processes might be helpful.by
Traumatic brain injury can cause post-traumatic neurodegenerations with an increase in reactive oxygen species and reactive oxygen species-mediated lipid peroxidation. Melatonin, a non-enzymatic antioxidant and neuroprotective agent, has been shown to counteract oxidative stress-induced pathophysiologic conditions like cerebral ischemia/reperfusion injury, neuronal excitotoxicity and chronic inflammation. Therefore, the research team at the Neuroscience Research Center, University of Suleyman Demire, led by Prof. Mustafa Nazıroğlu, aimed to evaluate whether there would be a protective effect of melatonin on oxidative stress and enzymatic and non-enzymatic antioxidant levels in traumatic brain injury rats.
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Higher levels of vitamin D in the blood are associated with a much better chance of surviving bowel cancer, scientists from Trinity College Dublin and the University of Edinburgh have discovered. The researchers analysed data from almost 1,600 patients treated for non-metastatic bowel cancer, i.e. bowel cancer that had not spread to other distant parts of the body. One in five, or 20% of the group with the lowest levels of vitamin D had died five years after diagnosis. However for those patients with the highest levels of vitamin D in their blood, 20% died ten years after diagnosis.
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Spanish scientists have demonstrated through an experiment on obese rats that the consumption of probiotics during thirty days helps diminish the accumulation of fat in the liver. This new finding, published by the journal PLOS ONE, is a great step forward on the fight against the Non-Alcolohic Fatty Liver Disease (NAFLD), which is closely related to obesity and diabetes. Researchers from the ‘Nutrition Biochemistry: Theurapetic Applications’ group (CTS-461) and the José Mataix Institute for Nutrition and Food Technology at the University of Granada have demonstrated that the administration of three probiotic strains diminishes the accumulation of fat in the liver of obese rats.
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Mice consuming a supplement of omega 3 fatty acids had healthier joints than those fed diets high in saturated fats and omega 6 fatty acids, according to Duke Medicine researchers. “Our results suggest that dietary factors play a more significant role than mechanical factors in the link between obesity and osteoarthritis,” said Farshid Guilak, Ph.D., Laszlo Ormandy Professor of Orthopaedic Surgery at Duke and the study’s senior author. Obesity is one of the primary risk factors for osteoarthritis, although the mechanisms linking these conditions are not fully understood. It has been assumed that increased weight wears the joints out, but this doesn’t explain why arthritis is also found in hands and other joints that don’t bear weight.
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Dozens of supplement ingredients have been touted for weight loss, but which have the strongest evidence showing they work and, among those, which products are highest in quality? To answer these questions, ConsumerLab.com, the independent health and nutrition product evaluator, reviewed the clinical evidence for more than 20 ingredients and tested the quality of more than 50 products. ConsumerLab found that no supplement has a large weight-loss effect, but certain ingredients may have a modest, short-term effect equating to 1 to 3 pounds lost in a month. From a quality standpoint, however, more than one-third of products used for weight loss have failed to pass ConsumerLab.com’s testing, most often for containing less of an ingredient than claimed.by