Glucosamine and Chondroitin Lower Mortality Rate 17%
Yes you heard it right at least according to a study in the American Journal of Clinical Nutrition of over 77,000 participants. The study looked at supplements use of the participants and followed the subjects for a 5 year timeframe. It was found in the study that glucosamine and chondroitin reduced risk of death (mortality) up to 17%.
Glucosamine is an amino sugar which helps to make up cartilage. In nature glucosamine is found in the hard outer shells of shrimp, lobsters and crabs. However it may also be made synthetically for people who have shellfish allergies. Glucosamine stimulates chondrocytes which may help in slowing cartilage breakdown. It is also seems that glucosamine inhibits interleukin (cause of inflammation) production. People taking glucosamine have reported mild stomach discomfort but other side effects appear to be limited. Glucosamine shouldn’t be taken with Warfarin. In the study on glucosamine’s effect on mortality it was found that death rate was reduced 8% in low usage of glucosamine supplementation up to 17% for high usage of glucosamine supplementation.
Chondroitin is a very large sized molecule. It is usually made from shark or pig cartilage. Chondroitin helps make up the matrix of the cartilage. Side effects are usually limited to mild stomach discomfort and chondroitin may also cause problems if taken with Warfarin. Chondroitin reduced risk of mortality from 12% for low usage to 17% for high usage.
It is thought that the reduction of mortality rate may be related to anti-inflammatory properties of both glucosamine and chondroitin.
I like to use the liquid form as it seems to be the best tolerated and I think seems to work better in patients. The one we use in the office is Tropical Oasis Liquid Glucosamine and Chondroitin. It seems to taste good and have a high compliance.
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