Researchers found that the protein, STING, may help treat or even avoid autoimmune diseases such as arthritis, type 1 diabetes and multiple sclerosis. Dr. Andrew L. Mellor, immunologist at the Medical College of Georgia at Georgia Regents University noted that the protein STING can turn down the immune response or even block its attack on healthy body constituents like collagen, insulin and the protective covering of neurons, all targets in these debilitating diseases. One question is the best way to activate STING. Mellor’s recently awarded $1.4 million grant from the National Institutes of Health should help answer that and more. Researchers will be comparing results from STING’s activation by DNA nanoparticles to its more direct stimulation by cyclic dinucleotides.
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