Choline is an essential nutrient involved in many body functions that is easily included in the diet through foods like liver, muscle meats, beans, peas, eggs, and more. Choline is important to the structure and function of cells. Choline is also the base for many metabolic functions of the body; helping to synthesis phosphatidyl choline, sphingomyelin, acetylcholine, and betaine. These nutrients are all crucial to the body for they support the neurotransmitters, the cell membranes, maintain homocysteine levels, and more.
Choline has been found to work well with B6, B12 and folic acid (through its metabolism to betaine) in connection to the metabolism of homocysteine. When used with methotrxate, choline metabolites may be reduced by the drug. Choline also has the potential to undo the fatty liver caused by methotrexate.
Choline, when taken in the proper dosage (up to 3 grams daily) is well tolerated by most people. There were a few reports of nausea and diarrhea. High doses of choline may cause a body odor, sweating, vomiting, and gastrointestinal distress.
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