Reduced Glutathione is an ubiquitous antioxidant involved in many cellular functions such as detoxification, amino acid transport, production of coenzymes and recycling of vitamins E and C. By serving as a critical nucleophilic scavenger, glutathione blocks free radical damage to all types of tissues. Glutathione is the most abundant intracellular thiol (sulfur-containing compound) and low molecular weight tripeptide found in living cells. Thiols such as glutathione, alpha lipoic acid and N-Acetyl -L-Cysteine (NAC) are powerful sulfur-bearing antioxidants. Glutathione can be found in fruits, vegetables and meats. The body also has the ability to produce glutathione in the liver. Glutathione is involved in many functions of the body. Proper amounts are crucial for maintaining good health although a deficiency may be noticed with age. Glutathione is involved in DNA creation and repair, the transport of amino acids, the metabolism of toxins and carcinogens, immune system function, the prevention of cell damage and more. Glutathione also demonstrates antioxidant activity, detoxification attributes, and immunomodulatory activity. Glutathione is connected to healthy well-being and healthy levels should be maintained.
Glutathione has recorded a positive interaction with cisplatin. When the two are used in conjunction, glutathione may help reduce the strength of cisplatin-induced nephrotoxicity and neurotocoicity without disrupting the efficiency of the drug. However, when glutathione is combined with either acetaminophen or alcohol, the drugs will decrease the therapuetic effects of the glutathione.
There have been no reported adverse effects when taking glutathione. For the most part, when recommended dosages were followed, glutathione was well tolerated.
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