Fibroblast Growth Factor

Fibroblast Growth Factor

Fibroblast Growth Factor (FGF) is one the most studied growth factor families. They are all protein growth factors and considered ligands. Originally, only two were identified FGF-1 and FGF-2, also known as acidic-FGF and basic-FGF. Since the first discovery, at least twenty more family members have been identified. FGFs play many important roles within the body, particularly with the cells. FGFs influene cell differentiation, migration, and mitogenesis.

There have also been four FGF receptors discovered. These receptors, FGFR1-4, also play key roles in the body.

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