Manganese is an essential trace mineral that can be found in nuts, legumes, seeds, teas, whole grains, and leafy green vegetables. Manganese is involved in several metabolic and enzymatic reactions, such as the metabolism of carbohydrates, amino acid, and cholesterol. It has the ability to hunt down hydroxyl and superoxide radicals. Manganese is also an important component of MnSOD, which is essential to the mitochondria defense system.
It is recommended that manganese not be combined with fluoroquinolones or tetracyclines due to a decrease in the absorption of the drugs. The use of calcium, IP-6, and iron may decrease the absorption of manganese by the body while zinc may help increase manganese absorption and levels.
Manganese is well tolerated by most people when taken in the proper dosage. If large amounts are used, there is an increased risk of neurotoxicity. Please consult a health care professional if you have liver disease and use with caution. As with all drugs and supplements, everyone should consult their health care professional.