According to Xyience Extreme Science, Sclareolude is a fermented sage compound (derived from Salvia sclarea, and sometimes called Sclareolude or Norambrolide) which activates the enzyme adenylate cyclase involved in the generation of a cellular messenger called cAMP (cyclic adenosine monophosphate). The significance of this is that cAMP is involved ub activating cellular enzymes and other substances that help move fat out of the fat cells and promote the weight loss process. Ephedrine has a similar effect in generating cAMP, but does so by acting as a stimulant to the adrenal glands. Sclareolude bypasses the adrenal glands, increasing cAMP levels directly without stimulant effects. The result is a safe and effective, natural ingredient for weight loss. Sclareolude activates a key enzyme responsible for increading metabolic rate and the release of fat from fat cells.