Glutamine has been considered nonessential for some time due to the ability of the body to create it. Glutamine is crucial to many body functions and levels should be maintained. Glutamine is actually the most abundant free amino acid in the body. It is primarily manufactured in the skeletal muscle, then released into circulation. Glutamine then becomes involved in the immune system, the gastrointestinal tract, the kidneys and the liver. The various body parts receive the glutamine through the blood. The glutamine can act as a transport for nitrogen and carbon. It can be metabolized for fuel and plays a role in the production of many other amino acids such as glucose, purines, glutamate, glutathione, and more. Glutamine is a very busy amino acid that is continually supporting the body for optimal health.
Glutamine should not be taken in conjunction to anticonvulsants or lactulose drugs due to negative reactions that may decrease effectiveness of drug. No other drug or supplement interactions have been recorded.
There have been no recorded side effects from glutamine at the time. However, there are some concerns about people, with neurological and psychiatric diseases, taking glutamine due to the metabolization of ammonia and glutamate which can stimulate neurological effects. As with all supplements and drugs, consult a health care professional.
View Research related to L-Glutamine.