Jarrow Formulas' pharmaceutical grade, stabilized SAM-e 400 is a full 400 mg elemental SAM-e from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated and foil blister packed to ensure a biologically active product.
SAM-e (S-Adenosylmethionine) is a chiral molecule and therefore consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.
Jarrow Formulas' SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e is an amino acid derivative that has been clinically proven to benefit brain, joint and liver function. Found in all living cells, SAM-e is also called activated methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM-e have identified the following benefits of SAM-e:
SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-dopa, and related hormones, epinephrine and phosphatidylcholine (a component of lecithin).
Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the process. Proper methylation through substances such as SAM-e positively influences longevity.
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.
1 Tablet, 30 servings per container
Microcrystalline cellulose, enteric coating (methacrylate copolymers), glycerol behenate, talc,triethylcitrate, glycerol palmitostearate, medium chain triglycerides, carboxymethylstarch sodium salt, silicon dioxide, titanium dioxide, magnesium stearate and riboflavin.
Take 1 tablet per day on an empty stomach, or as directed by your qualified health consultant.
Does Not Contain
No wheat, no gluten, no soy, no dairy, No egg, no fish/shellfish, no nuts/tree nuts.
Individuals using prescribed medications such as antidepressants, including Serotonin Re-Uptake Inhibitors and mao Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e. SAM-e 400 is foil blister-packed to maximize stability and safety. Do not use if seal of blister pack is broken. Store in a cool, dry place. Keep out of reach of children.
Serving Size is 1 Tablet*Daily Value (DV) not established.
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