Jarrow Formulas SAM-e 400 30 Tablets 790011200208

SAM-e 400 30 Tablets

by Jarrow Formulas

  • • 30 servings
Retail $39.95Regular $28.79$23.48

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Jarrow Formulas' pharmaceutical grade, stabilized SAM-e 400 is a full 400 mg elemental SAM-e from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated and foil blister packed to ensure a biologically active product.

SAM-e (S-Adenosylmethionine) is a chiral molecule and therefore consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.

Jarrow Formulas' SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.

SAM-e is an amino acid derivative that has been clinically proven to benefit brain, joint and liver function. Found in all living cells, SAM-e is also called activated methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM-e have identified the following benefits of SAM-e:

Joint Strength:

SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.

Brain Metabolism:

SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-dopa, dopamine and related hormones, epinephrine and phosphatidylcholine (a component of lecithin).


Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.


SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.

Serving Size

1 Tablet, 30 servings per container


S-Adenosyl-Methionine............. 400mg

Other Ingredients

Microcrystalline cellulose, enteric coating (methacrylate copolymers), glycerol behenate, talc,triethylcitrate, glycerol palmitostearate, medium chain triglycerides, carboxymethylstarch sodium salt, silicon dioxide, titanium dioxide, magnesium stearate and riboflavin.

Suggested Use

Take 1 tablet per day on an empty stomach, or as directed by your qualified health consultant.

Does Not Contain

No wheat, no gluten, no soy, no dairy, No egg, no fish/shellfish, no nuts/tree nuts.


Individuals using prescribed medications such as antidepressants, including Serotonin Re-Uptake Inhibitors and mao Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e. SAM-e 400 is foil blister-packed to maximize stability and safety. Do not use if seal of blister pack is broken. Store in a cool, dry place. Keep out of reach of children.

Supplement Facts

Serving Size is 1 Tablet
Amount Per Serving%DV
S-Adenosyl Methionine400mg*
*Daily Value (DV) not established.

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