Calcigard One-to-One provides equal amounts of calcium as calcium citrate, and magnesium as amino acid chelate, both with excellent bioavailability. Each batch of Calcigard One-to-One is certified by independent laboratory assay to be free of lead and other toxic heavy metals.
Amni® Calcigard® One-to-One, provided by Douglas Laboratories®, provides equal amounts of calcium as calcium citrate, and magnesium as amino acid chelate, both with excellent bioavailability. Calcigard™ Two-to-One provides calcium and magnesium in a 2:1 ratio from the same sources. Both formulas are available with and without added vitamin D. Calcigard tablets are formulated to disintegrate within 15 minutes or less following ingestion. Each batch of Calcigard One-to-One and Two-to-One is certified by independent laboratory assay to be free of lead and other toxic heavy metals.
The adult human body contains approximately 1,200 g of calcium, of which about 99% is present in the skeleton, and 20-30 g of magnesium with about 60% located in bone. The remaining 1% of total body calcium and 40% of total body magnesium are found in the soft tissues and play important roles in such vital functions as nerve conduction, muscle contraction, energy metabolism, blood clotting, membrane permeability, and hormonal signaling. Blood calcium levels are carefully maintained within very narrow limits by the interplay of several hormones (1,25-dihydroxycholecalciferol, parathyroid hormone, calcitonin, estrogen, and testosterone) which control calcium absorption and excretion, as well as bone metabolism. The intracellular levels of magnesium are also very tightly regulated, since their alterations can have profound effects on cardiac and skeletal muscle physiology. Intestinal calcium absorption ranges from 15 to 75% of ingested calcium. Adequate vitamin D status is necessary for normal calcium absorption. Magnesium absorption is independent of vitamin D status and ranges from 30 to 60% of ingested magnesium. Bone is constantly turning over, through a continuous process of formation and resorption. In children and adolescents, the rate of formation of bone mineral predominates over the rate of resorption. In later life, resorption predominates over formation. Therefore, in normal aging, there is a gradual loss of bone.
Osteoporosis afflicts a large proportion of the elderly in developed countries. Caucasian and Asian women typically have low peak bone densities, and are therefore at the greatest risk of developing osteoporosis. It is generally accepted that obtaining enough dietary calcium throughout life can significantly decrease the risk of developing osteoporosis. Among other factors, such as regular exercise, gender and race, calcium supplementation during childhood and adolescence appears to be a prerequisite for maintaining adequate bone density later in life. But even elderly osteoporotic patients can benefit significantly from supplementation with dietary calcium and magnesium. Calcigard One-to-One and Two-to-One provide highly beneficial sources of both calcium and magnesium. They are well absorbed and well tolerated. Calcium citrate, a highly bioavailable source of dietary calcium, is more completely absorbed than common calcium sources, such as calcium carbonate. Calcium citrate is also better tolerated than most forms of calcium. It does not give rise to intestinal gas production (due to release of carbon dioxide), bloating or constipation as is often experienced with other calcium preparations. Similarly, the magnesium amino acid chelate in Calcigard One-to-One and Two-to-One is well absorbed and generally well tolerated. Vitamin D (optional ingredient) is a key regulatory hormone for calcium and bone metabolism. Adequate vitamin D intake is important for ensuring normal calcium absorption and maintaining proper calcium plasma levels. People living in southern regions of the U.S. can derive significant amounts of vitamin D from sunlight dependent synthesis in the skin during the summer, whereas people in the northern states have to rely more on foods and supplements for adequate vitamin D status. This is why Calcigard formulas are available both with and without vitamin D.
1 tablet, 90 servings per container
modified cellulose gum,
Calcigard One-to-One: One to four tablets daily as a dietary
supplement, or as directed by a physician. Calcigard Twoto-
One: One to six tablets daily as a dietary supplement, or
as directed by a physician. Take with food. Individuals who
have trouble swallowing tablets may dissolve Calcigard
tablets in a glass of water or other suitable beverage.
Calcigard One-to-One and Two-to-One are generally safe and well tolerated. Excessive dietary calcium, i.e., intakes of 2,000 mg and more, may produce constipation and has no known further benefit to bone health. Excessive amounts of magnesium, such as 1,000 mg and more, may produce diarrhea.
Calcigard formulas should be used with caution by
individuals with hypercalcemia or serious renal
Serving Size is 1 tablet*Daily Value (DV) not established.
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