Calcigard 2 to 1 with Vitamin D 90 Tablets

Calcigard Two-to-One provides calcium and magnesium in a 2:1 ratio from the same sources. Calcigard tablets are formulated to disintegrate within 15 minutes or less following ingestion. Each batch of Calcigard Two-to-One is certified by independent laboratory assay to be free of lead and other toxic heavy metals.

Amni® Calcigard® One-to-One, provided by Douglas

Laboratories®, provides equal amounts of calcium as calcium

citrate, and magnesium as amino acid chelate, both with

excellent bioavailability. Calcigard™ Two-to-One provides

calcium and magnesium in a 2:1 ratio from the same sources.

Both formulas are available with and without added vitamin

D. Calcigard tablets are formulated to disintegrate within 15

minutes or less following ingestion. Each batch of Calcigard

One-to-One and Two-to-One is certified by independent

laboratory assay to be free of lead and other toxic heavy

metals.

The adult human body contains approximately 1,200 g of

calcium, of which about 99% is present in the skeleton, and

20-30 g of magnesium with about 60% located in bone. The

remaining 1% of total body calcium and 40% of total body

magnesium are found in the soft tissues and play important

roles in such vital functions as nerve conduction, muscle

contraction, energy metabolism, blood clotting, membrane

permeability, and hormonal signaling. Blood calcium levels

are carefully maintained within very narrow limits by the

interplay of several hormones (1,25-dihydroxycholecalciferol,

parathyroid hormone, calcitonin, estrogen,

and testosterone) which control calcium absorption and

excretion, as well as bone metabolism. The intracellular

levels of magnesium are also very tightly regulated, since

their alterations can have profound effects on cardiac and

skeletal muscle physiology.

Intestinal calcium absorption ranges from 15 to 75% of

ingested calcium. Adequate vitamin D status is necessary for

normal calcium absorption. Magnesium absorption is

independent of vitamin D status and ranges from 30 to 60%

of ingested magnesium.

Bone is constantly turning over, through a continuous

process of formation and resorption. In children and

adolescents, the rate of formation of bone mineral

predominates over the rate of resorption. In later life,

resorption predominates over formation. Therefore, in

normal aging, there is a gradual loss of bone.

Osteoporosis afflicts a large proportion of the elderly in

developed countries. Caucasian and Asian women typically

have low peak bone densities, and are therefore at the

greatest risk of developing osteoporosis. It is generally

accepted that obtaining enough dietary calcium throughout

life can significantly decrease the risk of developing

osteoporosis. Among other factors, such as regular exercise,

gender and race, calcium supplementation during childhood

and adolescence appears to be a prerequisite for maintaining

adequate bone density later in life. But even elderly

osteoporotic patients can benefit significantly from

supplementation with dietary calcium and magnesium.

Calcigard One-to-One and Two-to-One provide highly

beneficial sources of both calcium and magnesium. They are

well absorbed and well tolerated. Calcium citrate, a highly

bioavailable source of dietary calcium, is more completely

absorbed than common calcium sources, such as calcium

carbonate. Calcium citrate is also better tolerated than most

forms of calcium. It does not give rise to intestinal gas

production (due to release of carbon dioxide), bloating or

constipation as is often experienced with other calcium

preparations. Similarly, the magnesium amino acid chelate

in Calcigard One-to-One and Two-to-One is well absorbed

and generally well tolerated.

Vitamin D (optional ingredient) is a key regulatory hormone

for calcium and bone metabolism. Adequate vitamin D

intake is important for ensuring normal calcium absorption

and maintaining proper calcium plasma levels. People living

in southern regions of the U.S. can derive significant

amounts of vitamin D from sunlight dependent synthesis in

the skin during the summer, whereas people in the northern

states have to rely more on foods and supplements for

adequate vitamin D status. This is why Calcigard formulas

are available both with and without vitamin D.

Supplement Facts