Fundamental Sulfur 500 mg 100 Tablets

Fundamental Sulfur (MSM®) tablets provided by Advanced Medical Nutrition, each contain 500 mg of methylsulfonyl-methane (MSM). MSM, a derivative of DMSO, is a naturally occurring compound of biologically available sulfur. The essential trace element molybdenum is added as a cofactor for normal sulfur metabolism. Fundamental Sulfur also provides vitamin C, while Fundamental Sulfur II does not.

Sulfur is an indispensable element in human nutrition. As

part of the amino acids methionine and cysteine, sulfur is

required for the structural integrity and function of almost

every protein in the body, including enzymes, serum

proteins, and the keratin of skin, hair, and nails. Taurine,

another sulfur-containing amino acid is known for its role in

bile salt synthesis, cell membrane stability, neuronal

excitability and the regulation of osmotic pressure. Sulfur is

also an essential element for the glycosaminoglycans of

connective tissues and cartilage, and assumes a major role in

detoxification as part of the hepatic sulfur conjugation

pathways. Proper detoxification of xenobiotics, such as

phenols, and many endogenous and foreign food- or airborne

compounds depends on an adequate supply of

biologically active sulfur.

Dietary MSM serves as a versatile donor of metabolically

active sulfur for the synthesis of numerous organosulfur

compounds and proteins in the body. As such, MSM helps

maintain normal immune response, lung function,

connective tissue metabolism, and muscle contraction.

MSM occurs naturally in a variety of foods, such as fruits,

vegetables, cereal grains, milk, and fish. However, MSM is

volatile and easily lost during cooking. MSM is very well

absorbed by the intestinal tract and rapidly distributed within

the body.

Molybdenum is an essential trace element that assists in the

proper metabolism of sulfur. Specifically, molybdenum is

the cofactor of sulfite oxidase, an enzyme that converts potentially toxic sulfite to sulfate. This reaction is necessary

for the normal metabolism of the sulfur amino acids.

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