Studies have long demonstrated the benefits of gymnema
and fenugreek in maintaining healthy blood sugar
metabolism.† Recent studies indicate that cinnamon
may also play a critical role in blood sugar maintenance.†
Consuming large amounts of the spice cinnamon would
be difficult and have potentially adverse effects.
GlucoBrium™ contains Cinnulin PF®, a unique water-soluble
cinnamon extract that has been shown to safely
support blood sugar metabolism within the body.†
GlucoBrium is available in vegetarian capsules and
contains no animal derivatives.
GlucoBrium™, provided by Douglas Laboratories, supplies a synergistic
combination of Gymnema sylvestre, fenugreek and cinnamon extracts
designed to support healthy blood sugar metabolism.†
Glucose metabolism that is associated with abnormally high
blood glucose can lead to high levels of glycation. Glycation is the non-enzymatic
attachment of sugars to major molecules in the body, including proteins,
lipids, and nucleic acids. Glycation reactions generate advanced glycation
end-products (AGEs) and glycotoxin intermediates. AGEs cause abnormal
and destructive functioning of body proteins, lipids, and nucleic acids.
AGE-associated damage is suspected in age-related deteriorations.
Gymnema sylvestre is an Ayurvedic botanical that may assist in the normal
regeneration and development of healthy pancreatic beta cells.† Gymnema is
also suspected of reducing intestinal glucose absorption.† Native to India, this
woody, climbing plant has many traditional uses. Gymnemic acid, an active
component of Gynema sylvestre, has been identified in numerous animal studies
to help support healthy blood sugar levels. Human studies have indicated it
may be useful in healthy glucose metabolism.
Fenugreek, a popular spice in Asia and Europe, contains a high percentage
of mucilage, a soluble dietary fiber. Soluble dietary fiber plays important
roles in the digestive system, helping to inhibit the absorption of sugars and
fats and causing blood sugar levels to rise at a slower rate. Some animal
studies indicate that the active ingredient, 4-hydroxyisoleucine, may also play
important roles in supporting pancreatic beta-cells during insulin secretion.†
Human studies have also indicated that fenugreek plays supportive roles in
blood sugar metabolism and healthy cholesterol levels.†
Recently, cinnamon, a well-known spice and flavoring, has been gaining
attention for the role that it plays in supporting the body’s metabolism of glucose.
In one study, subjects given cinnamon showed significant decreases
in fasting glucose, triglycerides and cholesterol. Another study has indicated
that cinnamon may be a strong potentiator of insulin.† Interestingly, while
preliminary studies have identified methyl hydroxyl chalcone polymer(MCHP)
as the primary active ingredient, more recent studies have indicated that this
molecule may have been incorrectly identified. The active ingredients are
now believed to be primarily water-soluble proanthocyanidin type-A polymers.
Since proanothocyanidins have excellent antioxidant potential, cinnamon
may offer both the benefits of supporting blood sugar metabolism, as
well as providing significant antioxidant protection to the cell.†
While the safety of whole cinnamon spice is well known, there is some
concern that long term use of amounts greater than that used in cooking may
lead to potential toxic buildup.
GlucoBrium contains Cinnulin PF®, a patented water-soluble cinnamon
extract that is processed using a unique extraction method to remove any
potential toxins that whole cinnamon may contain.
Cellulose and vegetable stearate.
As a dietary supplement, adults take
1-2 capsules daily or as directed by physician.
yeast, wheat gluten, soy protein,
milk/dairy, corn, sodium, sugar, starch, artificial coloring,
preservatives or flavoring.
STORAGE: Store in a cool, dry place, away from direct light. Keep out of
reach of children.