GlucoBrium 60 VegiCaps

Studies have long demonstrated the benefits of gymnema

and fenugreek in maintaining healthy blood sugar

metabolism.† Recent studies indicate that cinnamon

may also play a critical role in blood sugar maintenance.†

Consuming large amounts of the spice cinnamon would

be difficult and have potentially adverse effects.

GlucoBrium™ contains Cinnulin PF®, a unique water-soluble

cinnamon extract that has been shown to safely

support blood sugar metabolism within the body.†

GlucoBrium is available in vegetarian capsules and

contains no animal derivatives.

GlucoBrium™, provided by Douglas Laboratories, supplies a synergistic

combination of Gymnema sylvestre, fenugreek and cinnamon extracts

designed to support healthy blood sugar metabolism.†

Glucose metabolism that is associated with abnormally high

blood glucose can lead to high levels of glycation. Glycation is the non-enzymatic

attachment of sugars to major molecules in the body, including proteins,

lipids, and nucleic acids. Glycation reactions generate advanced glycation

end-products (AGEs) and glycotoxin intermediates. AGEs cause abnormal

and destructive functioning of body proteins, lipids, and nucleic acids.

AGE-associated damage is suspected in age-related deteriorations.

Gymnema sylvestre is an Ayurvedic botanical that may assist in the normal

regeneration and development of healthy pancreatic beta cells.† Gymnema is

also suspected of reducing intestinal glucose absorption.† Native to India, this

woody, climbing plant has many traditional uses. Gymnemic acid, an active

component of Gynema sylvestre, has been identified in numerous animal studies

to help support healthy blood sugar levels. Human studies have indicated it

may be useful in healthy glucose metabolism.

Fenugreek, a popular spice in Asia and Europe, contains a high percentage

of mucilage, a soluble dietary fiber. Soluble dietary fiber plays important

roles in the digestive system, helping to inhibit the absorption of sugars and

fats and causing blood sugar levels to rise at a slower rate. Some animal

studies indicate that the active ingredient, 4-hydroxyisoleucine, may also play

important roles in supporting pancreatic beta-cells during insulin secretion.†

Human studies have also indicated that fenugreek plays supportive roles in

blood sugar metabolism and healthy cholesterol levels.†

Recently, cinnamon, a well-known spice and flavoring, has been gaining

attention for the role that it plays in supporting the body’s metabolism of glucose.

In one study, subjects given cinnamon showed significant decreases

in fasting glucose, triglycerides and cholesterol. Another study has indicated

that cinnamon may be a strong potentiator of insulin.† Interestingly, while

preliminary studies have identified methyl hydroxyl chalcone polymer(MCHP)

as the primary active ingredient, more recent studies have indicated that this

molecule may have been incorrectly identified. The active ingredients are

now believed to be primarily water-soluble proanthocyanidin type-A polymers.

Since proanothocyanidins have excellent antioxidant potential, cinnamon

may offer both the benefits of supporting blood sugar metabolism, as

well as providing significant antioxidant protection to the cell.†

While the safety of whole cinnamon spice is well known, there is some

concern that long term use of amounts greater than that used in cooking may

lead to potential toxic buildup.

GlucoBrium contains Cinnulin PF®, a patented water-soluble cinnamon

extract that is processed using a unique extraction method to remove any

potential toxins that whole cinnamon may contain.

Supplement Facts