Pan-Ox-5™, provided by Douglas Laboratories, is a
synergistic dietary enzyme formula that is specially
formulated for digestive support.
The pancreas supplies the major digestive enzymes
that catalyze the breakdown of starches
(carbohydrates), proteins, and fats, so that the
breakdown products can be absorbed in the upper
small intestine.
Some carbohydrate digestion takes place in the mouth
by salivary amylase, but pancreatic amylase is the
major carbohydrate-digesting enzyme. Amylases
break down starches to maltose and maltotriose,
which are further hydrolyzed into glucose by the
disaccharidases of the mucosal cells, and then
absorbed. Although cellulose is indigestible by
pancreatic and intestinal enzymes, the microflora
within the large intestine may degrade it and produce
uncomfortable symptoms in the process.
Although fat digestion starts in the mouth with the
action of salivary lipase, the great majority of fat
triglycerides are digested by pancreatic lipase secreted
by the exocrine pancreas into the duodenum. Lipases
break down triglycerides into monoglycerides and
free fatty acids, which are efficiently absorbed in the
upper small intestine.
Protein digestion is initiated in the stomach by pepsin
and hydrochloric acid, which denature and break
large proteins down to smaller polypeptides. In the
small intestine, proteases break down these
polypeptides into free amino acids, and di- and
tripeptides, which are directly absorbed by the
intestinal mucosa.
Ingredients such as aspergillus oryza, ox bile extract
and rennin can also aid in the digestion and
absorption of food.
Adults take 1 tablet daily with meals or as directed by
physician.