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Niacin is a water soluble B vitamin whose main role is to serve as a precursor for two essential biochemical coenzymes, nicotinamide adenine dinucleotide (NAD) and NAD phosphate (NADP). These two cofactors participate in virtually every aspect of the energy production and metabolic processes. Consequently, Niacin nutriture has been shown to impact many areas of human health. NAD functions in reactions involving the degradation (catabolism) of carbohydrates, fats, and proteins to produce energy. Niacin is also critical for DNA replication and repair, and therefore plays a critical role in genetic stability. In addition, Niacin has been shown to have a number of beneficial effects on lipid and cholesterol transport, and thus is important for the maintenance of healthy serum lipid levels that are already within the healthy range. Inositol Hexanicotinate is a stable, non-flushing source of Niacin. This superior source of Niacin works to reduce the common "niacin-flush" problems associated with high doses of Niacin supplements.*
Niacin, also called Vitamin B3, is one of eight water-soluble B vitamins. B vitamins, often referred to as B complex vitamins, are essential cofactors for the production of cellular energy from carbohydrate, protein and fats. Niacin is normally found in milk, eggs, meat, poultry, fish, whole grains and other foods that contain protein, although its more convenient use as a supplement has grown dramatically in recent years.
At least 200 enzymes are known to be dependent on Niacin and its active forms, NAD and nicotinamide. Therefore, Niacin nutriture has an impact on many areas of human health, especially in energy and biosynthetic pathways. Niacin has been found to support a healthy nervous system and is critical for the maintenance of DNA stability. In addition, there is extensive clinical evidence that indicates that high-dose niacin can support healthy serum lipid levels that are already within the healthy range.*
Taking high doses of Niacin can cause a "flushing" sensation, which is not harmful, but may be unpleasant. Protocol for Life Balance™ Flush Free Niacin is a form called inositol hexaniacinate, the form of niacin that has been found to be best tolerated, and causes the least flushing symptoms.
1 , 90 servings per container
Cellulose (capsule), Stearic Acid (vegetable source), Magnesium Stearate (vegetable source), Rice Flour and Silica.
Inositol Hexanicotinate is a stable, non-flushing source of Niacin. This superior source of Niacin works to reduce the common "niacin-flush" problems associated with high doses of Niacin supplements.
As a dietary supplement, take 1 Vcap® daily as needed, preferably with meals. For intensive use, take 1-2 Vcaps® twice daily, under the supervision of a health care practitioner.
Does Not Contain
sugar, salt, yeast, wheat, gluten, corn, soy, milk, egg or preservatives
The Institute of Medicine of the NIH has established the Tolerable Upper Intake Level (UL) for all forms of niacin for adults as 35 mg/day based on flushing as the critical adverse effect. The form of niacin in this product however, is unlikely to cause a flushing response.
High dose niacin has been associated with liver inflammation. Although some reports suggest that it occurs most commonly with slow-release niacin, it can occur with any type of niacin when taken at a daily dose of more than 500 mg (usually 3 g or more). Regular blood tests to evaluate liver function are therefore mandatory when using high-dose niacin (or niacinamide or inositol hexaniacinate).
The antituberculosis drug isoniazid (INH) may increase the need for niacin.
If you have liver disease, ulcers (presently or in the past), gout, gallbladder disease, or drink too much alcohol, do not take highdose niacin except on medical advice.
High-dose niacin may interact with statin drugs (the most effective medications for high cholesterol). This combination therapy could contribute to the potentially fatal condition called rhabdomyolysis, and should be attempted only under the supervision of a physician.
Niacin may interfere with the absorption of Tetracycline, and therefore the two should be taken at different times of the day.
Not to be used by pregnant/lactating women or those with liver problems, stomach ulcers or diabetes unless recommended by your healthcare practitioner.
Serving Size is 1 *Daily Value (DV) not established.
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