Pycnogenol is a natural plant product made from the bark of European
coastal pine, Pinus maritima. Pycnogenol is rich in proanthocyanidins, a special class of
water-soluble antioxidant flavonoids which are excellent free radical scavengers. Numerous
scientific studies have demonstrated that Pycnogenol helps to maintain vascular strength
and function. In addition, Pycnogenol has been shown to support a healthy, balanced
Rutin and Acerola have been added as synergists.
Pycnogenol® is a proprietary and patented water extract of the bark of the French maritime
pine, which is grown in coastal south-west France. Pycnogenol contains oligomeric
proanthocyanidins (OPCs) as well as several other bioflavonoids: catechin, epicatechin,
phenolic fruit acids (such as ferulic acid and caffeic acid), and taxifolin.
The unique combination of constituent phytochemicals and OPCs in Pycnogenol is what
gives it its four basic properties – it is a powerful antioxidant, it helps to maintain a balanced
inflammatory response, it selectively binds to collagen and elastin, and finally, it aids in the
production of endothelial nitric oxide which helps to regulate blood flow.
Numerous studies have been conducted on Pycnogenol demonstrating its remarkable
properties. Pycnogenol® has been shown to support cardiovascular and vein health,
cognitive function, balanced inflammatory response, and healthy respiratory function.
Pycnogenol may also benefit skin health through its ability to protect collagen, thereby
playing a role in the maintenance of skin elasticity. Because it enhances microcirculation,
skin stays well nourished and shielded from the destructive effects of UV light.
Cellulose (capsule), Cellulose and Magnesium Stearate (vegetable source).
As a herbal dietary supplement, take 1 capsules 1 to 3 times daily.
Increase dose as directed by a health care professional.
sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg, shellfish or preservatives.
If you are taking blood thinning medications, high doses of OPCs might increase the risk of
In theory, Pycnogenol® may alter blood sugar levels. Caution is advised in patients with
diabetes or hypoglycemia, and in those taking drugs, herbs, or supplements that affect
blood sugar. Medication adjustments may be necessary.
Pycnogenol® is generally reported as being well tolerated. Because of its astringent taste
and occasional minor stomach discomfort, it may be best to take Pycnogenol® with or after
meals. To date, no serious adverse effects have been reported in the available scientific
literature, although a systematic study of safety is not available.